WebTalk:CTGF. This article is within the scope of WikiProject Molecular and Cell Biology. To participate, visit the WikiProject for more information. This article has been rated as Stub … WebConnective tissue growth factor (CTGF) is a member of the recently described CCN gene family which contains CTGF itself, cyr61, nov, elm1, Cop1, and WISP-3. CTGF is transcriptionally activated by several factors although its stimulation by transforming growth factor beta (TGF-beta) has attracted considerable attention.
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WebThe bona fide YAP/TAZ target genes are connective tissue growth factor (CTGF) and cysteine-rich angiogenic inducer 61 (CYR61) ( Zhao et al., 2008 ). CYR61 and CTGF are CCN family (CYR61, CTGF, and NOV proteins) … WebConnective tissue growth factor: a fibrogenic master switch in fibrotic liver diseases. Liver Int. 2008 Sep;28 (8):1065-79; Gygi D, Zumstein P, Grossenbacher D, Altwegg L, Luscher TF, Gehring H. Human connective tissue growth factor expressed in Escherichia coli is a non-mitogenic inhibitor of apoptosis. Biochem Biophys Res Commun. 2003 Nov 21 ...
WebWord definitions in dictionaries Wikipedia. CTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein).CTGF has important roles in many biological processes, including cell adhesion, migration, … WebJun 26, 2024 · Connective tissue growth factor (CTGF) or cellular communication network 2 (CCN2) is a matricellular protein essential for normal embryonic development and tissue repair. CTGF exhibits cell- and context-dependent activities, but CTGF function in vascular development and barrier function is unknown. We show that endothelial cells (ECs) are …
WebCTGF (98 a.a.), a lower molecular weight isoform containing the C-terminal portion of the full length CTGF protein, exerts full heparin binding, cell adhesion, and mitogenic CTGF activity. Mature Human CTGF is a 38.0 kDa secreted protein containing 323 amino acid residues. CTGF is comprised of four distinct structural domains (modules), which ... WebJun 6, 2012 · CTGF is a secreted matricellular protein with very complex biology. It has been shown to modulate many signaling pathways leading to cell adhesion and migration, angiogenesis, myofibroblast activation, and extracellular matrix deposition and remodeling, which together lead to tissue remodeling and fibrosis.
WebJun 6, 2012 · Key roles for connective tissue growth factor (CTGF/CCN2) are demonstrated in the wound repair process where it promotes myofibroblast differentiation and angiogenesis. Similar mechanisms are active in tumor-reactive stroma where CTGF is expressed. Other potential roles include prevention of hypoxia-induced apoptosis and …
WebOct 26, 2024 · Idiopathic pulmonary fibrosis (IPF) is a type of chronic lung disease that causes progressively worsening dyspnea (shortness of breath). People with IPF may also experience a dry and persistent cough, progressive fatigue, or unexplained weight loss. bioinformatics technical electivesWebCTGF, also known as CCN2 or connective tissue growth factor,[5][6] is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins … dailyinfo jobs uk oxfordWebConnective tissue growth factor, also known as CCN2, is a cysteine-rich matricellular protein involved in the control of biological processes, such as cell proliferation, differentiation, … bioinformatics technicianWebConnective tissue growth factor (CTGF), also termed fisp12, βIG-M2, and IGF-BP8, is a secreted cysteine-rich growth factor that belongs to the CCN (cyr61, CTGF, nov) family. … daily info houses to rent in oxfordWebApr 5, 2008 · - Answers What is the value of Harrington and Richardson Arms 32 caliber SW ctgf? Wiki User ∙ 2008-04-05 04:50:14 Study now See answer (1) Best Answer Copy Ranging in price from $100 to $300,... bioinformatics systemsWebMar 10, 2024 · As a secreted matricellular protein in the extracellular matrix (ECM), CTGF functions primarily by interacting with cell surface receptors, growth factors, and cytokines [ 2 ]. CTGF is involved... bioinformatics technician jobsCTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein). CTGF has important roles in many biological processes, including cell adhesion, migration, … See more Members of the CCN protein family, including CTGF, are structurally characterized by having four conserved, cysteine-rich domains. These domains are, from N- to C-termini, the insulin-like growth factor … See more Knockout mice with the Ctgf gene disrupted die at birth due to respiratory stress as a result of severe chondrodysplasia. Ctgf-null mice also show defects in angiogenesis, with impaired interaction between endothelial cells and pericytes … See more • Human CTGF genome location and CTGF gene details page in the UCSC Genome Browser. See more CTGF is associated with wound healing and virtually all fibrotic pathology. It is thought that CTGF can cooperate with TGF-β to … See more • Ctgf/hcs24 CAESAR • CYR61 (CCN1) See more bioinformatics technician job description