Hif1a分子量
Web9 de dez. de 2024 · The transcription factor HIF1A is a canonical master-regulator of hypoxic signaling, translocating to the nucleus under hypoxic conditions and regulating multiple pathways, including angiogenesis... Web本抗体是以人HIF-1αaa432-528一段多肽为抗原制备的小鼠单克隆抗体,然后用protein A和抗原亲和柱经过两步纯化得到的高纯度抗体。
Hif1a分子量
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Web1 de set. de 2010 · Our recent studies have mechanistically implicated a loss of stromal Cav-1 expression and HIF1-alpha-activation in driving the cancer-associated fibroblast phenotype, through the paracrine production of nutrients … Web17 de ago. de 2024 · To investigate whether HIF1A loss correlates with altered inflammation, we first demonstrated that HIF1A loss tumours exhibit on average between 1.9- and 2.1-fold higher levels of mRNA of CD3D ...
Web7 de jul. de 2024 · Asiatic acid (AA) could attenuate ischemia/reperfusion induced myocardial apoptosis through upregulating the Akt/GSK-3β/HIF-1α pathway. HIF-3α is a negative regulator of HIF-1α, whose mRNA is a potential target of miR-1290. AA could upregulate miR-1290 in non-small-cell lung cancer A549 cells. Web26 de fev. de 2024 · The competence of tumor cells to endure oxygen depletion is largely due to accumulation of Hypoxia-inducible factor 1 (HIF-1), a transcription factor consisting of an O 2 -responsive HIF-1α subunit...
WebMonoclonal Antibody for studying HIF2-alpha. Cited in 67 publications. Validated for Western Blotting. Highly specific and rigorously validated in-house, HIF-2α (D9E3) Rabbit Monoclonal Antibody (CST #7096) is … Web25 de mai. de 2024 · Therapeutic targeting of the androgen signaling pathway is a mainstay treatment for prostate cancer. Although initially effective, resistance to androgen targeted therapies develops followed by disease progression to castrate-resistant prostate cancer (CRPC). Hypoxia and HIF1a have been implicated in the development of resistance to …
Web21 de mar. de 2024 · HIF1A (Hypoxia Inducible Factor 1 Subunit Alpha) is a Protein Coding gene. Diseases associated with HIF1A include Retinal Ischemia and Enchondromatosis, …
Web腫瘍細胞の低酸素応答研究に有用 HIF1α 抗体. HIF1a 抗体(anti HIF1a antibody)は、HIF1a タンパク質を検出するウサギポリクローナル抗体です。. 低酸素条件下で誘導される転写因子である HIF1α を検出します。. how many seasons in outer banksWebHIF1A(Hypoxia-inducible factor 1-alpha)是由 826 个氨基酸组成的大小为 90.6KD 蛋白质。 HIF1A亚基由bHLH结构域、PAS结构域、ODD结构域以及反式激活结构域四部分共同组 … how did circleville ohio get its nameWeb26 de jul. de 2016 · Background: Hyperthermia is a promising treatment for human lung cancer, but recurrence of the primary lesion is common, as the residual tumor becomes … how many seasons in mindhunterWebFigure 2. HIF1A protein in macrophages is elevated in hemophagocytic lymphohistiocytosis (HLH) mouse models. (A) Schematic diagram depicting lymphocytic choriomeningitis virus (LCMV)-infected Prf1 − / − HLH mouse model. Perforin-deficient (Prf1 − / −) mice were infected with or without LCMV-WE of 200 plaque-forming units (PFU) via intraperitoneal … how many seasons in peaky blindershow many seasons in portlandiaWebEoE patient biopsy analysis identified a repressed HIF-1α/claudin-1 axis, which was restored via pharmacologic HIF-1α stabilization ex vivo. Collectively, these studies reveal HIF-1α’s critical role in maintaining barrier and highlight the HIF-1α/claudin-1 axis as a potential therapeutic target for EoE. Graphical Abstract. how did cisco dieWebCITED2(216-246):Hif1a(796-826L822A) (Homo sapiens), CBP (340-439) (Mus musculus) Wright Add to Cart Sign Up for Our Newsletter. Receive the latest news, hot plasmids, discounts and more. Sign Up. Subscribe to Our Blog. Learn about the latest plasmid technologies and research tools. ... how many seasons in obx