WebHigh-fat diet leads to development of cardiac dysfunction through molecular mechanisms poorly known. The aim of this study is to elucidate the early events in … Web6 de jan. de 2024 · Antrodan Alleviates High-Fat and High-Fructose Diet-Induced Fatty Liver Disease in C57BL/6 Mice Model via AMPK/Sirt1/SREBP-1c/PPARγ Pathway Int J …
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Webhigh-fat diet: A diet rich in fats, especially saturated (animal or tropical oils) fats. High-fat diets are ill-advised for those with arthritis, cancer, cardiovascular disease, diabetes, … Web11 de abr. de 2024 · The increase in metabolic diseases including insulin resistance, metabolic syndrome, and diabetes mellitus worldwide is largely attributable to the global … philinthegaps.as.me
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Web10 de abr. de 2024 · The abnormal level of FXR, miR-34a and SIRT1 emerges in mice fed a high-fat diet, indicating these mediators could be associated with lipid and cholesterol metabolism [30]. Therefore, this study proposed a FXR/miR-34/SIRT1 regulatory loop for NAFLD treatment and designed OCA and anta-miR-34a co-delivery nanovesicle to … Web18 de jun. de 2024 · Combining a High Dose of Metformin With the SIRT1 Activator, SRT1720, Reduces Life Span in Aged Mice Fed a High-Fat Diet The Journals of Gerontology: Series A Oxford Academic Abstract. SRT1720, a sirtuin1-activator, and metformin (MET), an antidiabetic drug, confer health and life-span benefits when … Web29 de abr. de 2024 · Six to eight week old mice were fed a high-fat diet (HFD) and randomly assigned to one of the following groups: (1) wild-type mice (wt+HFD), (2) Sirt1 … philinthegaps