Web27 iun. 2024 · Multiple myeloma (MM) is a plasma cell disorder characterized by clonal proliferation of malignant plasma cells producing … Web29 nov. 2024 · Multiple myeloma (MM) is a type of blood cancer that affects white blood cells called plasma cells. These cells help to fight infection. In MM, the abnormal plasma …

Myeloma and the kidney

WebMultiple myeloma can affect the kidney in several ways. It can affect the filter (glomerulus), the tubules (pipes), or the tissue of the kidney itself (interstitium). … WebAcum 1 oră · READ MORE: Onward in the Fight Against Multiple Myeloma. OM-301 works by binding to HDM2, a protein found on the surface of myeloma cells, then binding to an … dahua technology ip camera

Myeloma Kidney - StatPearls - NCBI Bookshelf

Web5 feb. 2024 · Hypercalcemia in multiple myeloma can occur as a result of dysregulated bone turnover, leading to the secretion of osteoclast-activating and osteoblast-inhibiting factors. Hypercalcemia can lead to vasoconstriction of the renal blood vessels, which in turn reduces blood flow in the kidney. Web9 iul. 2015 · It is associated with both liquid malignancies, commonly multiple myeloma, leukemia, and non-Hodgkins lymphoma and solid cancers, particularly breast and renal carcinomas as well as squamous cell carcinomas of any organ. ... is the preferred bisphosphonate in patients with normal to moderately impaired renal function. With … Web• Monoclonal gammopathies including multiple myeloma are a large spectrum of disorders. • In monoclonal gammopathy with normal renal function, PC-AKI risk is not increased. • Renal function is often reduced in myeloma, increasing the risk of PC-AKI. • Correction of hypercalcaemia is necessary in mye … dahua technology internal portal